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Phentermine primarily works through central appetite suppression via norepinephrine release, while tirzepatide operates through incretin-based pathways affecting both peripheral and central appetite regulation, glucose metabolism, and gastric motility

This communication happens via the gut-brain axis, a complex network linking the digestive system and the central nervous system

p = 0.0009), reflecting an 87% decrease in risk

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GLP-1 and endometriosis-related cancer risk A recent study examined the effects of GLP-1 receptor agonists on incident gynecologic cancer outcomes in endometriosis patients compared to metformin