Vitamin D: Supports immunity and bone health, especially for those with limited sun exposure
Collagen supplementation: Oral collagen peptides (10-15g daily) provide specific amino acids (glycine, proline, hydroxyproline) enriched in connective tissue
SLC3A1 has been indicated to promote the proliferation of stem cells in hepatocellular carcinoma cells (53) and was evidenced to be an effective therapeutic target in metastatic colorectal cancer through the recognition of metabolic signatures specific to metastatic cell lines (54)

ALA may be helpful for: People with diabetic neuropathy: ALA has the strongest clinical evidence for reducing nerve pain and improving quality of life in this group.1 Those with type 2 diabetes or metabolic syndrome: Modest improvements in insulin sensitivity and blood sugar markers have been observed in some studies.24 People with high oxidative stress: Research shows that ALA can help lower oxidative stress markers like CRP in individuals with chronic inflammation or metabolic risk factors.27 Those with nerve-related conditions or mitochondrial dysfunction: Early research suggests ALA may help support nerve health in contexts like multiple sclerosis.3 However, ALA may not be appropriate if: Youre generally healthy and eat a balanced diet Your body naturally produces some ALA, and small amounts are found in foods like spinach, broccoli, red meat, and organ meats.41 In healthy individuals, taking an ALA supplement may offer little to no added benefit

10.1097/MCC.0b013e32834e7c3a 27 HrelecM.KlicekR.BrcicL.BrcicI.CvjetkoI.SeiwerthS.et al (2009)