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Current serotonin medications are aimed at increasing central 5-HT neurotransmission in the brain, and there are no approved indications for manipulating peripheral 5-HT, though peripheral 5-HT synthesis is being considered as a potential target for developing pharmacological agents in some disorders (8, 9)

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Similar content being viewed by others Subjects Main Glutathione (GSH) is a small peptide (l--glutamyl-l-cysteinyl glycine) that can react as a nucleophile or a reducing agent

IV glutathione compares to oral supplements with higher bioavailability but poorer clinical outcomes and safety

Here we show that depletion of intracellular GSH does not alter tumour growth and extracellular GSH is highly abundant in the tumour microenvironment, highlighting the potential importance of GSH outside tumours