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Am J Clin Nutr 89(1):425
Pairing a GHRH analogue with a GHS-R1a agonist is a long-standing design in secretagogue research, following the work of Bowers and colleagues showing that the two classes produce a greater combined response than either alone
Additionally, they exert anti-inflammatory effects by enhancing the number of Treg cells and promoting the production of anti-inflammatory factors, such as IL-4 and IL-10 (129, 130)
LC also affects mitochondrial activity by boosting mitochondrial biogenesis and decreasing oxidative stress
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