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For an RUO page, literature should be interpreted as background for model design, pathway language, and documentation review

Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a

Compared to longer or modified neuropeptides, DSIP retains a compact sequence with broad receptor interaction potential

The picture changes substantially for non-topical routes

[1] Properties of Ipamorelin Nasal Spray: Molecular Formula: CHNO Molecular Weight: 711.9 g/mo CAS Number: 170851704 PubChem CID: 9831659 Synonyms: Ipamorelin, NNC260161 Research Applications/Benefits of Ipamorelin Nasal Spray Growth Hormone Signaling Studies: Ipamorelin is widely used to examine GHS-R1a-mediated GH release mechanisms in cellular and preclinical models