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These compounds are used to modify a carboxyl group to form an amine-reactive ester

Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. Hypertension 54.3 (2009): 567-574

The difference between 10 mg and 15 mg was less than 2 percentage points of additional weight loss, which for many people does not justify the increased side effect burden