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GLP-1 Medications Affect Men and Women Differently Heres Why That Matters GLP-1 medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounarjo, Zepbound) can do a lot often, a whole lot to help manage conditions like obesity and diabetes and improve overall metabolic health

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Because they can be viscous these fibers have bulking effects and slow gastric emptying, which can also contribute to feeling fuller for longer, he observes

It mimics the action of endogenous GLP-1, a hormone released by the intestines in response to food intake

"These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones," says Jena Shaw Tronieri, Senior Research Investigator at Penn's Center for Weight and Eating Disorders and a co-author of the study