5-Amino-1MQ targets NNMT, an enzyme that consumes S-adenosylmethionine (SAM), the cell's principal methyl donor
Vitamin B12 injections are generally safe, but some people may experience side effects, such as pain, redness, or swelling at the injection site, mild headaches, dizziness, nausea, or itching
Individuals taking metformin alongside Mounjaro face higher B12 deficiency risk and may require more frequent monitoring
Pro tip: Pair with NAD+ boosters and a clean, protein-rich diet to support cellular energy and fat oxidation
NNMT inhibition increases intracellular NAD+ by blocking nicotinamide methylation, but the long-term metabolic consequences of sustained NNMT suppression