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bioRxiv (Cold Spring Harbor Laboratory) 2023
Zinkel, S
The short answer: yes, for most people
Upregulation of Nrf2 is an adaptive mechanism in the absence of Cpt1a To evaluate the importance of Nrf2 in Cpt1a-deficient cells, we employed two potent inhibitors of Nrf2, Brusatol and ML385, with distinct mechanisms of action 54,55
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