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Small molecule GLP-1 agonists and antagonists (such as those in development at Structure Therapeutics) may facilitate study of endogenous GLPs activity and increase clinical uptake in T2D and obesity patients

Wegovy (semaglutide 2.4mg weekly injection) carries the chronic weight management indication

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In recent years, the remarkable effectiveness of these medications for significant weight loss has made brand names like Ozempic household words- and led to 13-17% of the U.S