doi:10.3389/fphar.2023.1327230 17
Evidence from both preclinical and clinical studies supports their antiinflammatory roles in the cardiovascular system, liver, kidneys, and joints
Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19
Treatment with the selective GLS1 inhibitor BPTES reduced glycolysis and ameliorated lupus-like disease and EAE in MRL/lpr mice ( + CD4 - CD8 - cells), the urinary albumin/creatinine ratio, glomerular nephropathy score, and T-cell infiltration with IL-17A in the kidneys, relieving the EAE disease activity ( + T cells by inhibiting GLS1, glycolysis, and CD4 + T-cell differentiation in vitro by reducing the level of HIF1 protein, a key metabolic sensor in Th17 cells ( Table 1 )
Clay particles carry a negative surface charge, allowing them to bind positively charged toxins through electrostatic interactions