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A genome-wide methylation analysis revealed that high IMF levels were highly correlated with the hypermethylation of the promoters of three genes: ATP binding cassette subfamily A member 1 ( ABCA1 ), COL6A1 , and glutathione S-transferase theta 1-like ( GSTT1L )
*Correspondence: Roberta Poli, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Clinical Diabetes, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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Unlike E3 and E4 mice, in E2 mice plasma acylcarnitines, particularly LCAs, remained elevated with age and overall higher than in other genotypes regardless of age
