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Oral Semaglutide: PIONEER-1 and Beyond The PIONEER-1 clinical trial evaluated once-daily oral semaglutide across multiple dosing groups over 26 weeks

Trigger Beverages Coffee (both regular and decaffeinated) Alcohol Carbonated beverages (soda, sparkling water) Mint tea (surprisingly, mint can relax the valve between your stomach and esophagus) Other Common Triggers Chocolate Onions and garlic (especially raw) Peppermint Foods That Are Easier on Your Stomach Focus on foods that are less likely to trigger reflux: Lean Proteins Skinless chicken breast Turkey Fish (baked or grilled, not fried) Egg whites Whole Grains Oatmeal Brown rice Whole grain bread Quinoa Vegetables (non-acidic) Leafy greens Broccoli Cauliflower Cucumbers Green beans Potatoes (baked or boiled, not fried) Fruits (non-citrus) Bananas Melons Apples Pears Healthy Fats in Moderation Avocado (small amounts) Olive oil (used sparingly) Nuts and seeds (small portions) Lifestyle Modifications Stay Hydrated Drink plenty of water throughout the dayaim for more than 2-3 liters daily

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Dehkhoda F, Lee CMM, Medina J, Brooks AJ