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How to Administer a B12 injection to Yourself There are two ways to self-inject vitamin B12: Subcutaneously, or just below the skin, and intramuscularly, which goes directly into the muscle, says Foxx
Most practitioners recommend starting at 250-300 mcg daily to assess tolerance, then potentially increasing to 400-500 mcg if initial response is suboptimal and no side effects occur
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For severe deficiencies, especially those with neurological symptoms, a full resolution of symptoms might take several weeks or even months of consistent treatment
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