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More studies are needed in preterm infants to know whether routine supplementation of L-carnitine in neonates requiring total parenteral nutrition for a long time would provide any clinical benefit
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Its a cAMP-biased agonist, meaning it emphasizes metabolic and appetite-regulating pathways while minimizing receptor desensitization and gastrointestinal side effects (Chen et al., 2023)
Similarly, mice lacking the melanocortin-4 receptor eat primarily fat and are unaffected by MT-2
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