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[3] This was based on data in an article that concluded "DPP-4 inhibition with saxagliptin did not increase or decrease the rate of ischemic events, though the rate of hospitalization for heart failure was increased
Patients on lower starting doses (such as the 0.25 mg microdose protocol) often experience gentler symptoms compared to standard 1 mg weekly injections
What the Pivotal Trial Actually Measured STEP 1 enrolled 1,961 adults with a body mass index of 30 or greater, or 27 or greater with at least one weight-related coexisting condition, none of whom had diabetes
Journal of Clinical Medicine, 13(18), 5627
If maximum average weight loss is the goal Tirzepatide's dual-receptor mechanism is linked to greater average weight loss in head-to-head trial data, at the cost of a shorter approval track record
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