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149,150 In addition to its role in the pancreas, stimulating GLP-1R provides further protective benefits in vascular tissues by decreasing ROS-related harm in endothelial cells

However, try to avoid taking it alongside a high-protein meal, as the enzymes produced to digest that protein might still interfere with the supplements absorption

The modest heart rate increase of 5-10 beats per minute appears tolerable in most patients

For patients with diabetes, dehydration poses additional risks by potentially affecting kidney function and blood glucose stability

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