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After blocking, the membrane was incubated overnight at 4 C with the specified primary antibodies, including TRPM2 antibody at a dilution of 1:1000 and GAPDH antibody at a dilution of 1:3000

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14,49,50 Although an imbalance in AEs related to diabetic retinopathy was not observed with oral semaglutide compared with placebo (7.1% and 6.3%, respectively) in PIONEER 6, the study excluded patients with proliferative retinopathy or maculopathy

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Action: Stimulates the synthesis of growth hormone by increasing intracellular cAMP