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Regulation: Apart from destroying free radicals and reactive oxidants, glutathione engages in thiol protection and redox regulation of cellular thiol proteins under oxidative stress by protein S-glutathionylation, a redox-regulated post-translational thiol modification
& Rosen, E
These studies revealed that GSH metabolism plays an important role in tumor initiation and progression, but the role played by GSH and the mechanism of GSH action in GC remain unclear
the compound's evidence base is limited to preclinical in vitro and animal (largely rodent) studies of IGF-1 receptor activation, muscle-cell signaling, and tissue repair, with human safety and efficacy data for this specific analog effectively absent
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