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A recent study published in Diabetes Obesity and Metabolism found that individuals using these medications lost significant amounts of fat but also experienced some degree of muscle loss, with lean body mass reductions making up approximately 25%40% of total weight Trusted Source Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies Neeland IJ, Linge J, Birkenfeld AL Go to Source loss

Gastroenterol Hepatol (NY)

Long-term use requires careful monitoring for metabolic complications including diabetes and osteoporosis

Part A 15, 263742 (2009)

If you cant afford it, the manufacturer has assistance programs that may help reduce the cost for eligible patients