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Chronic inflammation (due to poor diet, infections, stress, etc.) can deplete levels and has been implicated with higher levels of TPO antibodies, as well as higher TSH
Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestations
It is a poorer fit, or warrants caution, in patients with known sulfur or sulfite sensitivity, in poorly controlled asthma, and in anyone whose expectations are anchored to unproven claims particularly cosmetic skin-lightening