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SURMOUNT-1 applied similar exclusions [10]
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This leads to decreased peripheral and central 5-HT levels, impaired receptor function, reduced concentrations of tryptophan and 5-HT (232), worsened symptoms of affective disorders, elevated levels of tryptophan catabolites (233, 234), and increased concentrations of toxic metabolites in the CNS (235)
Once reconstituted, store refrigerated and use within appropriate timeframes
Now research is starting to investigate the area more systematically
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