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J Nutr (2015) 145(9):204651.10.3945/jn.115.210617 39 JacknessCKarmallyWFebresGConwellIMAhmedLBesslerMet alVery low-calorie diet mimics the early beneficial effect of Roux-en-Y gastric bypass on insulin sensitivity and beta-cell function in type 2 diabetic patients
Its what allows the peptide to bind to its target receptors and produce a biological effect
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