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It seems that obesity plays an important role in the pathophysiology of migraine as well, with obese women having elevated plasma levels of calcitonin gene-related peptide (CGRP) compared to controls [32, 33]

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Many of these preexisting T cells target conserved epitopes within human coronaviruses, suggesting that they were induced by previous seasonal HCoV infection [62, 94]

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Median CAP indices were 311 and 284 ( p = 0.04) and the median LSM scores were 7.8 and 5.8 ( p = 0.02) in patients treated with conventional and triple therapy, respectively