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Human cytomegalovirus protein US2 interferes with the expression of human HFE, a nonclassical class I major histocompatibility complex molecule that regulates iron homeostasis

Moreover, there might be other microbial contributors for converting BB to TMA which also requires to be elucidated [2]

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These mice survived for a total of 25 days and naturally died, which we defined as the survival endpoint as illustrated in Fig