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A self-reinforcing cycle may develop Reduced mitochondrial efficiency may increase oxidative stress
Furthermore, the potent antioxidant capacity of ascorbate can cause Fe 3+ to change into Fe 2+ via Fentons reaction
Renal transporters may facilitate drugs to enter the tubular cells, sometimes followed by metabolism leading to their bioactivation (Liang et al
Iron River, WI 54847 (715) 372-5590 (715)372-5590 www.northlandvet.net Cobalamin (Vitamin B12) In animals with reduced cobalamin absorption, regardless of the cause, it is reasonable to expect that eventual depletion of cobalamin body stores will occur and cobalamin deficiency will ensue
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