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6.1 Carbohydrate needs: timing, type and quantity Performance during endurance and intensive training can be greatly improved by consuming a diet heavy in carbs

Danuglipron made it further to Phase IIb, but Pfizer ended the entire program in April 2025 after a single asymptomatic case of potential drug-induced liver injury and dropped its third oral candidate a few months later

It works well as a skin-enhancing nutrient when used in combination with a balanced diet

Weight-loss medications are the most commonly excluded category

Recent studies suggest that GLP-1 RAs could improve renal function in patients with chronic kidney disease (CKD) and DM2 (33, 34)