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12 The trial was powered to test noninferiority of semaglutide versus placebo on cardiovascular outcomes for the purpose of regulatory approval
When examining different thresholds for MPR, a clear trend was apparent with larger difference in fracture risk for increasing MPR thresholds between the GLP-1 RA group and the DPP-4i group
The glucagon component may contribute an additional vasodilatory effect that amplifies the blood pressure benefit relative to GLP-1-only compounds
The collapse of both astrocyte and microglia into pro-inflammatory states due to depletion of GSH, leading to sustained neuroinflammation and oxidative stress, is observed in many neurodegenerative diseases (Ferreira et al., 2013
excursions permitted to 15C to 30C (59F to 86F) [see USP Controlled Room Temperature]
