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The most common adverse reactions include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, which occur as expected consequences of delayed gastric emptying and are typically transient

To further evaluate the effects of GLP-1 analogs on muscle mass, four types of skeletal muscles (soleus, gastrocnemius, tibialis anterior, and extensor digitorum longus) were independently measured after 3 weeks of treatment

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J Chromatogr B BioMed Sci Appl

(2019) further showed that exercise induces endogenous MOTS-c translocation to the nucleus, where it regulates stress-adaptive gene expression [6]