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Treatment aims are mainly to prevent hemolytic crises and correction of acidosis

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While topical skincare alone cannot prevent these changes, preserving muscle helps maintain the underlying structure that supports the skin

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Evidence supports even simple activities like: Higher daily step counts Resistance training to preserve lean mass Maintaining muscle to support metabolic health (muscle burns more resting calories) Optimize Medication Dose Maximum average weight loss in GLP-1/GIP clinical trials occurred at higher doses