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By combining Keap1 inhibitors with H2S-donor moieties via molecular hybridization, DDO-1901 showed enhanced efficacy in alleviating colitis by mitigating oxidative stress and inflammation, outperforming parent drugs alone (263)
It suggested that the pelvic environment in endometriosis is actively depleted of a hormone with known anti-inflammatory properties
10.1016/j.bbcan.2019.04.005 130 NozhatZ.Mohammadi-YeganehS.AziziF.ZarkeshM.HedayatiM
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