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A study that followed 1,156 patients with severe obesity for 12 years found those who underwent gastric bypass surgery at the beginning of the study maintained an average weight loss of 35 kg while those who did not have surgery maintained an average weight loss of 02.9 kg

doi: 10.4331/wjbc.v10.i1.7

6 As discussed, weight loss often includes muscle loss, and preserving muscle is vital for maintaining metabolic rate (the number of calories burned at rest), physical strength, and function, and potentially reducing the risk of weight regain

The higher dosing in Wegovy (2.4 mg weekly) compared to Ozempic's maximum diabetes dose (1.0 mg weekly) provides superior weight loss results

And you can certainly lose a lot of weight on semaglutide