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However, current evidence on GLP-1 agents is largely observational and hypothesis-generating
Trial populations were predominantly conducted in North American settings with specific demographic characteristics that may limit generalisability
Human clinical trials establishing these effects have not been completed and conclusions about efficacy in humans should not be drawn from this data alone
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PubMed Randomized trialTirzepatide evidence2025 Tirzepatide for Obesity Treatment and Diabetes Prevention Supports newer discussion of obesity treatment and diabetes-prevention outcomes
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