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Ultimately, the evolving competitive landscape will require Soleno to invest in post-marketing evidence, targeted physician engagement, and differentiation strategies to retain leadership in this rare but high-need therapeutic area

The honest answer depends on rate of weight loss, baseline nutritional status, and liver function markers

Recent studies show that semaglutide may play a positive role in heart health

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The largest semaglutide trial showed that patients regained two-thirds of lost weight in a year, although a study of electronic medical records showed regain of only a third of lost weight