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The meta-analysis by Tuersun found no significant difference in body weight reduction when comparing the combination therapy to either GLP-1RA monotherapy or SGLT2i monotherapy: this finding challenges the assumption of a synergistic or additive effect on weight loss [15]

Therefore, there is a growing need to explore pharmacological approaches to aid weight loss in individuals with the diabesity syndrome

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Mutationen im Gen fr Aquaporin-2 knnen zu einem schweren renalen (die Nieren betreffenden) Diabetes insipidus fhren