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Putting the Evidence in Context The relationship between GLP-1 medications and optic nerve disease has been debated since 2024, when a team at Massachusetts Eye and Ear first reported a possible link with semaglutide

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When an E/M service and a procedure are submitted for the same enrollee on the same date of service, there is a presumption that the E/M service is part of the procedure unless the physician identifies the E/M service as a separately identifiable service

This stability means that a single daily administration is sufficient for virtually all research protocols

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