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These changes are directly linked to declining oestrogen levels, which affect how your body handles glucose and stores fat

MAFG-driven astrocytes promote CNS inflammation

Tirzepatide (Mounjaro, Zepbound) is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

Noom emphasizes choosing foods with a low calorie density, which may be an effective strategy for weight loss

Additionally, semaglutide has been shown to have a comparable risk profile to other GLP-1 RAs with respect to gastrointestinal adverse effects in the IBD population (106)