GLP-1s seem to offer some benefit in brain health, says McIntyre
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Combining them allows for a more comprehensive GH modulation, supporting both immediate and sustained benefits across fat metabolism, recovery, and overall vitality
GLP-1RAs, which increase satiety and reduce hunger and increasing satiety could exacerbate dietary restriction (i.e., physiological undereating) and dietary restraint (i.e., the cognitive effort to reduce food intake) by encouraging the adoption of extreme and rigid dietary rules (see Figure 1)
The results were mixed: in some studies, lean mass was largely stable, while others saw more notable reductions