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Weight loss can decrease the bodys fat percentage, which in turn can reduce estrogen levels, potentially leading to lighter periods, irregular cycles, or even amenorrhea (absence of menstruation)
If you are exploring other diabetes treatment options, reading about what Trulicity is can give you a sense of how another GLP-1 works and whether it might fit your situation better
Fatigue may occur because the body is adjusting to treatment, but it may also reflect under-eating, low protein intake, dehydration, electrolyte changes, rapid weight loss, poor sleep, constipation, low blood sugar, low blood pressure, or another medical issue