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Dietary choline or trimethylamine N-oxide supplementation does not influence atherosclerosis development in Ldlr-/- and Apoe-/- male mice

This study for the first time makes a comparison of the molecular and kinetic properties of e-GSTs from seven different mammal species

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Potential targets being explored for AD gene therapies include amyloid pathway intermediates and the modulation of enzymes, tau protein downregulation, APOE4 downregulation and APOE2 upregulation, neurotrophin expression, and inflammatory cytokine alteration (Lennon et al., 2021)