By potentially protecting the compressed nerve from further damage and supporting its regeneration, it could address the sciatica and neuropathy components of the injury
As integral components of the NVU, perivascular astrocytes maintain BBB characteristics by contributing to basement membrane formation, regulating pericyte differentiation, and modulating EC functions by regulating the expression of TJs such as claudin-5, occludin, and ZO-1 [49, 51,52,53]
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The Journal of Clinical Endocrinology and Metabolism, 59 (1), 127-132