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However, neither the innate nor the adaptive immune response is affected by the DPP-4 inhibitors being used clinically (128), and reassuringly, there is no evidence for any increased risk of infections in the pooled safety analyses (119123) or in the CV safety outcome trials (125127), in line with the view that the catalytic activity of DPP-4 is not necessary for the co-stimulatory role of CD26 in T-cell activation

To view a copy of this licence, visit About this article Cite this article Taki, N., Doosti, A

Wash your hands thoroughly with warm water and soap for at least 20 seconds

Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes

This can contribute to additional weight gain