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While consensus does not exist regarding the exact synergistic mechanisms by which dual-agonists work, the addition of GIP agonism is posited to improve the HbA1c control and weight loss offered by GLP-1 agonists alone by enhancing insulin secretion, decreasing energy consumption, and stimulating satiety in the hypothalamus

In a city like Los Angeles, where people are often balancing work, traffic, travel, and personal obligations, choosing a longer treatment session can feel like a welcome change of pace rather than another task on the calendar

Investigation findings

[1] If diarrhoea is severe or persistent, your prescriber may recommend remaining at your current dose for an additional week or two before increasing, allowing your digestive system more time to adapt