When complexed with copper(II), the GHK-Cu complex has been studied as a modulator of extracellular matrix remodeling, antioxidant response, and gene expression programs related to tissue repair
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It removes the dependency on conversion and reduces the likelihood of metabolic bottlenecks
Apart from the truncation at the N-terminus SnCE1 104-310 and the mutant SnCE1 104-310 C256A recapitulate all effects observed for the longer SnCE1 construct, i.e., SnCE1 74-310