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"It is therefore recommended that higher thresholds are proposed for fermentation products which can be used for the US market." "In the European market the EMA guideline on setting specifications for related impurities in antibiotics (EMA/CHMP/CVMP/QWP/199250/2009 corr) published 30 June 2012, includes a special threshold for fermentation products," the company added

Oral supplementation is commonly used as a first-line approach

Prescription Medication Policy - Vetmeds

The USP specification calls for sterile, non-pyrogenic water with 0.9% benzyl alcohol as preservative, in a glass multi-dose vial with metal crimp seal

Deepa M, Farooq S, Datta M, Deepa R, Mohan V