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Typically, patients experienced a reduction of 1 to 3 kilograms in weight
In the COMBINE 2 trial in individuals with T2D inadequately controlled with GLP-1RA, with or without additional oral glucose-lowering medications, IcoSema as compared to semaglutide 1.0 mg provided superiority in HbA 1c reduction from baseline to week 52 and greater improvement in fasting plasma glucose with comparable rate of combined clinically significant or severe hypoglycemia, while the weight change was in favor of semaglutide 1.0 mg [14]
FDA-approved for type 2 diabetes, it delivers strong blood sugar control alongside significant weight loss
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