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Rapid free fatty acid mobilization without adequate glycogen stores may trigger reactive hypoglycemia in susceptible individuals

We also introduced R242E, K244E, and R249E point mutation or R242E/K244E/R249E triple mutation to the K2 domain of HGF, and showed that all the HGF-K2 mutants exhibited lower potency in activating c-MET as compared with wild-type HGF (Fig

Four isoforms of human glutaminase are divided into two highly active renal glutaminase types encoded by GLS1 and two low active hepatic glutaminase types encoded by GLS2

She adds that starting with a lower dose of 2 mg/week instead of 4 mg/week may help mitigate adverse effects