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doi: 10.1016/S0149-2918(98)80104-5 176 KaleagasiogluFOlcayE

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Quick Takeaways Ipamorelin creates a more physiologic and pulsatile GH release, with fewer systemic hormonal disruptions MK-677 reliably elevates GH and IGF-1, improves sleep, and increases lean mass at the expense of hammering insulin sensitivity Neither compound is FDA-approved for anti-aging optimization or physique enhancement