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These hydroxylation reactions also require Fe 2+ as a cofactor, O 2 as a cosubstrate and ascorbic acid (vitamin C) as a reductase, which restore the activity of 2-OGDD enzymes (Fig

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11 Conclusion In this paper, we have investigated the role of deuterium in mitochondrial dysfunction, and the potential role of amyloidogenic proteins in sequestering deuterium within plaque deposits, both in the brain and in the pancreas

Maes M, Crespo Yanguas S, Willebrords J, Weemhoff JL, da Silva TC, Decrock E, Lebofsky M, Pereira IVA, Leybaert L, Farhood A, Jaeschke H, Cogliati B, Vinken M