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Clinical Evidence: No IGF-1 Changes Human clinical trials measured serum IGF-1 levels at baseline and throughout treatment with AOD-9604 at various doses

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This means TRIUMPH-3 cannot confirm cardiovascular benefit that question is reserved for the dedicated TRIUMPH-Outcomes trial (~10,000 participants), not expected until 20282029

If the data for the SUMMIT trial is already available, why waste the effort to get the FDA approval

The outcomes look encouraging, but additional extensive trials are in progress